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Methods for Selecting Phage Display Antibody Libraries

[ Vol. 22 , Issue. 43 ]

Author(s):

Ricardo Jara-Acevedo, Paula Diez, Maria Gonzalez-Gonzalez, Rosa Maria Degano, Nieves Ibarrola, Rafael Gongora, Alberto Orfao and Manuel Fuentes   Pages 6490 - 6499 ( 10 )

Abstract:


The selection process aims sequential enrichment of phage antibody display library in clones that recognize the target of interest or antigen as the library undergoes successive rounds of selection. In this review, selection methods most commonly used for phage display antibody libraries have been comprehensively described.

Keywords:

Phage display, antibody, antigen, epitope.

Affiliation:

, , , , , , , Department of Medicine and General Cytometry Service-Nucleus, Cancer Research Center (CSIC/USAL/IBSAL), 37007 Salamanca



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