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Assessment of Memory Impairment in Early Diagnosis of Alzheimer’s Disease

[ Vol. 16 , Issue. 11 ]

Author(s):

Martin Vyhnálek*, Hana Marková, Jan Laczó, Rossana De Beni and Santo Di Nuovo   Pages 975 - 985 ( 11 )

Abstract:


Memory impairment has been considered as one of the earliest clinical hallmarks of Alzheimer’s disease. This paper summarizes recent progress in the assessment of memory impairment in predementia stages. New promising approaches of memory assessment include evaluation of longitudinal cognitive changes, assessment of long-term memory loss, evaluation of subjective cognitive concerns and testing of other memory modalities, such as spatial memory. In addition, we describe new challenging memory tests based on memory binding paradigms that have been recently developed and are currently being validated.

Keywords:

Elderly, memory impairment, Alzheimer's disease, mild cognitive impairment, subjective cognitive decline, neuropsychological assessment, memory binding, spatial memory.

Affiliation:

Memory Clinic, Department of Neurology, Charles University, 2nd Faculty of Medicine and Motol University Hospital, Prague, Memory Clinic, Department of Neurology, Charles University, 2nd Faculty of Medicine and Motol University Hospital, Prague, Memory Clinic, Department of Neurology, Charles University, 2nd Faculty of Medicine and Motol University Hospital, Prague, Department of Psychology, University of Padua, Padua, Department of Education, University of Catania, Catania



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