Maryam Sabbaghan and Zinatossadat Hossaini Pages 745 - 748 ( 4 )
N-alkyl 2-[(2-oxo-2-aryl ethyl)amino] benzamide derivatives have been synthesized in high yields. This involves three-component reaction of isatoic anhydride, primary amines in the presence of 2-bromoacethophenone derivatives. The reaction workup is simple and the products can be easily separated from the reaction mixture.
2-bromoacethophenone, Benzamide, green synthesis, one-pot synthesis, solvent-free, Isatoic Anhydride, Primary Amines, Diversity-oriented synthesis (DOS), heterocycles compound, pharmacological properties
Chemistry Department, Faculty of Sciences, Shahid Rajaee Teacher Training University, P.O. Box 16785-163, Tehran, Iran.