Saeed Balalaie, Ahmad Khazaie and Morteza Ashouriha Pages 845 - 850 ( 6 )
An efficient protocol for the synthesis of dihydropyrano [2,3-c] chromenes derivatives by one-pot threecomponent reaction of aromatic aldehydes, malononitrile or methyl cyanoacetate, and 4-hydroxy coumarin has been developed using catalytic amount (10%) of three different catalysts piperidine, triethyl amine, and natrium carbonate in aqueous media. The present protocol has significant features such as easy set-up and work-up, environmentally benign, high yields, short reaction times.
Aqueous media, Dihydropyrano[2, 3-c]chromenes, Natrium carbonate, One-pot three-component reaction, Piperidine, Triethyl amine.
Peptide Chemistry Research Center, K. N. Toosi University of Technology, P. O. Box 15875-4416, Tehran, Iran.