Zinatossadat Hossaini, Samereh Seyfi, Faramarz Rostami-Charati and Mehdi Ghambarian Pages 788 - 790 ( 3 )
A water-accelerated multicomponent synthesis of organic target molecules has been used as a key method for the preparation of novel imidazole derivatives. The three-component condensation reactions of primary amines with trichloroacetonitrile in the presence of ninhydrine in water are developed as efficient and clean green synthetic procedures for the high-yielding preparation of imidazoles.
Indenoimidazole, Ninhydrine, Primary amines, three-component reaction, trichloroacetonitrile.
Department of Chemistry, Qaemshahr Branch, Islamic Azad University, Qaemshahr, Iran.