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Synthetic Applications of Polystyrene-Supported 1,1,3,3-Tetramethylguanidine

[ Vol. 11 , Issue. 10 ]


Alberto Coelho, Abel Crespo, Franco Fernandez, PierFrancesco Biagini, Angela Stefanachi and Eddy Sotelo   Pages 843 - 847 ( 5 )


Several applications of polystyrene-supported 1,1,3,3-tetramethylguanidine (PS-TMG) in synthetic organic chemistry have been explored. This study evidenced the effectiveness and versatility of this new member of the supported guanidine superbases as an attractive candidate to replace the bases usually employed in organic synthesis during the implementation of environmentally friendly preparative processes.


Supported reagents, TMG, base


Unidad de Quimica Combinatoria, Instituto de Farmacia Industrial (IFI), Universidad de Santiago de Compostela, Santiago de Compostela, 15782, Spain.

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